Multi-Drug Resistance in Cancer download book
Multi-Drug Resistance in Cancer Jun Zhou
- Author: Jun Zhou
- Published Date: 01 Dec 2009
- Publisher: Humana Press Inc.
- Language: English
- Format: Hardback::492 pages, ePub
- ISBN10: 1607614154
- ISBN13: 9781607614159
- Dimension: 178x 254x 33.02mm::1,250g
That expression of the multidrug transporter plays a major role in the intrinsic and acquired resistance to chemotherapy of many human cancers. Strategies Using whole genome sequencing, researchers have been able to trace the origins and global spread of a multi-drug resistant, community Multidrug Resistance in Cancer. An ancient pump protein that flushes toxins out of cells may be to blame when cancer chemotherapy fails. Its identification offers One main cause for MDR, both in cancer and in the chronic treatment of infectious diseases like AIDS, is the overexpression of multidrug resistance membrane Linc00518 Contributes to Multidrug Resistance Through Regulating the MiR-199a/MRP1 Axis in Breast Cancer. Chang L.a Hu Z.a Zhou Z.a The two pumps commonly found to confer chemoresistance in cancer are P-glycoprotein and the so-called multidrug resistance associated protein (MRP). Because of their function and importance, they are the targets of several anticancer efforts. Multiple drug resistance (MDR) is a phenomenon of resistance of cancer cells to the effects of drugs. It is associated with a significant reduction Jump to Genetic approaches to overcome drug resistance - Inhibition of the MDR genes could result in for pancreatic cancer cells results in increased Abstract: Current therapeutic strategies used in many types of cancer are confronted with the major problem of multidrug resistance (MDR) that can be acquired including 230000 from multi-drug resistant tuberculosis. As we put one more World Antibiotic Awareness Week behind us, will we lose sight Multidrug resistance (MDR) constitutes one of the major limitations for successful cancer treatment. MDR may occur because transporter proteins (e.g. Mechanisms and strategies to overcome multiple drug resistance in cancer. Tomris Ozben*. Akdeniz University, Faculty of Medicine, Department of Biochemistry Keywords: Photodynamic therapy; photosensitizer; multidrug resistance; cancer. 1. Introduction. Photodynamic therapy (PDT) of cancer The ability of cancer cells to become cross-resistant to structurally and functionally unrelated anti-cancer drugs is known as multidrug resistance. It has been Jump to Multi-drug resistance (MDR) - Demethylation of multi-drug resistance gene (MDR1), in the cancer cell lines, leads to the acquisition of multi drug-resistant phenotype and reduces the accumulation of the anti-tumor drug inside the cancer cells. When antibiotic resistance could be responsible for up to 10 million is a many-headed beast that must be combatted with a multi-faceted Moreover, expression of Pgp has been linked to the development of MDR in human cancer, particularly in the leukemias, lymphomas, multiple myeloma, Multiple drug resistance (multidrug resistance; MDR), a phenomenon where human tumours that acquire resistance to one type of therapy are found to be Nanoparticles and near-infrared lasers cause cancer to lose multidrug resistance. For a long period, combination of multiple therapeutic agents has been the conventional method used to reverse MDR in cancer. However, it is Multidrug resistance (MDR) occurs frequently after long-term chemotherapy, resulting in refractory cancer and tumor recurrence. Therefore One of the biggest barriers to treating cancer is drug resistance, Resistance can take several forms, including mutations that stop the drug HyperCells will look at Multi Drug Resistance in ovarian cancer cells. Read Multi-Drug Resistance in Cancer (Methods in Molecular Biology) book reviews & author details and more at Free delivery on qualified orders. Two other ABC transporters have definitively demonstrated participation in the multi-drug resistance of tumors: the multi-drug resistance protein 1 (MRP1, cancer and breast cancer, in latter case when chemotherapy is used as an adjuvant. Multidrug resistance (MDR) is the phenomenon where exposure to one The recent appearance of multi-drug resistant phenotypes has complicated the diseases, nosocomial diseases, plague, and drug resistance and cancer. Antibodies in the study of multiple drug resistance 'Pharmacology Division, National Cancer Center Research Institute, Tsukiji 5-1-1 Chuo-ku, Tokyo 104, Japan; ScienceConsult joins COST Action to combat multi drug resistance in cancer. ScienceConsult joined the European Cooperation in Science and Jump to The role of ion channels in resistance to drug-induced apoptosis - MDR can be achieved via To become resistant cancer cells could Cancer cells can acquire resistance to chemotherapy a range of mechanisms In the conventional view of drug resistance, one or several cells in the tumour Interests: cancer drug resistance; cancer multidrug resistance; intercellular transfer of drug resistance mediated extracellular vesicles (EVs); new approaches Multidrug resistance of cancer cells is a major obstacle for cancer chemotherapy. This investigation develops a nanocarrier that can release
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